Faculty Information : Hamamatsu University School of Medicine

Basic information on teaching staff

Other affiliation

[1]. Hamamatsu University School of Medicine Vice President for Research

Career

1987/- 1997/ 萬有製薬(株)つくば研究所
1997/- 2000/ 九州大学
2000/- 浜松医科大学

Academic degrees

Ph.D. The University of Tokyo

Research Areas

Life Science - Tumor biology

Life Science - Molecular biology

Life Science - Functional biochemistry

Life Science - Cell biology

Life Science - Medical biochemistry

Subject of research

[1]. 細胞運命決定機構の研究、ユビキチンシステムの研究、長鎖ノンコーディングRNAの研究、エピゲノム研究、細胞周期制御機構の研究、癌抑制遺伝子産物の機能と制御機構の研究

Research activities

Papers

[1]. Expression of Tumor Suppressor FHIT Is Regulated by the LINC00173-SNAIL Axis in Human Lung Adenocarcinoma.
International journal of molecular sciences [Volume]24 [Issue]23 [Page]17011 （2023/） [Reviewed] Yes [DOI]

[2]. CCIVR2 facilitates comprehensive identification of both overlapping and non-overlapping antisense transcripts within specified regions.
Scientific reports [Volume]13 [Issue]1 [Page]14807 -14807 （2023/） [Reviewed] Yes [DOI]

[3]. p130RB2 positively contributes to ATR activation in response to replication stress via the RPA32-ETAA1 axis
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Elsevier BV [Volume]1870 [Issue]6 [Page]119484 -119484 （2023/） [Reviewed] Yes [DOI]

[4]. APOBEC3B expression is promoted by lincNMR collaborating with TGF-β-Smad pathway.
Carcinogenesis （2022/） [Reviewed] Yes [DOI]

[5]. Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair.
Biochimica et biophysica acta. Molecular cell research [Volume]1869 [Issue]11 [Page]119332 （2022/） [Reviewed] Yes [DOI]

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Research presentations

[1]. 2019/10/16 Long noncoding RNA ELIT-1 act as a Smad3 cofactor to promotes TGFbeta-Smad signaling and epithelial-mesenchymal transition EMBO Workshop The Non-Coding Genome

[2]. 2019/9/28 A novel lncRNA ELIT-1 promotes Snail induction and EMT via TGFb signaling 第78回日本癌学会学術総会

[3]. 2019/9/18 TGF βによって誘導され、TGF β-Smadシグナリングの正の制御因子として機能する新規lncRNA ELIT-1 第92回日本生化学会大会

[4]. 2019/7/19 Smad3の標的遺伝子へのリクルーターとして機能する新規lncRNA ELIT-1 第21回日本RNA学会年会

[5]. 2018/10/14 SCF-Skp2 E3 ligase is involved in progression of lung fibrosis and is a potential molecular target for IPF therapy BIT's 10th Annual World Congress of Molecular & Cell Biology

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Memberships of academic societies

[1]. JAPAN SOCIETY FOR CELL BIOLOGY

[2]. 日本分子生物学会

[3]. 日本癌学会

[4]. 日本生化学会

[5]. 日本RNA学会

Committee Career

[1]. 2001/4/1- 日本生化学会評議委員

Educational activities

Allotted class

[1]. 生化学

[2]. 光医工学共同専攻「生体構造・機能解析」

[3]. 先端基礎医学特論

[4]. 分子基礎医学I

[5]. 分子基礎医学

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