医学部 医学科 総合人間科学 生物学
教授
マエダ タツヤ
前田 達哉

更新日: 2026/06/18
論文
[1]. Function of the 30kd protein of tobacco mosaic virus: involvement in cell-to-cell movement and dispensability for replication
EMBO J [巻]6 [頁]2557 -2563 (1987年) [査読] 有
[2]. Mutations in the Tobacco Mosaic Virus 30-kD Protein Gene Overcome Tm-2 Resistance in Tomato
Plant Cell [巻]1 [頁]515 -522 (1989年) [査読] 有
[3]. Adenylyl cyclase is dispensable for vegetative cell growth in the fission yeast Schizosaccharomyces pombe
Proc. Natl. Acad. Sci. USA [巻]87 [頁]7814 -7818 (1990年) [査読] 有 [DOI]
[4]. Schizosaccharomyces pombe ste11+ encodes a transcription factor with an HMG motif that is a critical regulator of sexual development
Genes & Dev [巻]5 [頁]1990 -1999 (1990年) [査読] 有 [DOI]
[5]. Characterization of a fission yeast gene, gpa2, that encodes a Gα subunit involved in the monitoring of nutrition
Genes & Dev [巻]6 [頁]2455 -2462 (1992年) [査読] 有 [DOI]
[6]. Mutations in a Protein Tyrosine Phosphatase Gene (PTP2) and a Protein Serine/Threonine Phosphatase Gene (PTC1) Cause a Synthetic Growth Defect in Saccharomyces cerevisiae
Mol. Cell. Biol. [巻]13 [頁]5408 -5417 (1993年) [査読] 有
[7]. Cloning of the pka1 gene encoding the catalytic subunit of the cAMP-dependent protein kinase in Schizosaccharomyces pombe.
The Journal of biological chemistry [巻]269 [号]13 [頁]9632 -7 (1994年) [査読] 有
[8]. A two-component system that regulates an osmosensing MAP kinase cascade in yeast
Nature [巻]369 [頁]242 -245 (1994年) [査読] 有 [DOI]
[9]. Activation of Yeast PBS2 MAPKK by MAPKKKs or by Binding of an SH3-Containing Osmosensor
Science [巻]269 [頁]554 -558 (1995年) [査読] 有 [DOI]
[10]. Cloning and characterization of seven cDNA for hyperosmolarity-responsive (HOR) genes of Saccharomyces cerevisiae
Mol. Gen. Genet. [巻]249 [頁]127 -138 (1995年) [査読] 有 [DOI]
[11]. Yeast HOG1 MAP Kinase Cascade Is Regulated by a Multistep Phosphorelay Mechanism in the SLN1-YPD1-SSK1 "Two-Component" Osmosensor
Cell [巻]86 [頁]865 -875 (1996年) [査読] 有 [DOI]
[12]. Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases
Mol. Cell. Biol. [巻]17 [頁]1289 -1297 (1997年) [査読] 有
[13]. Protein phosphatase 2Cα inhibits the human stress-responsive p38 and JNK MAPK pathways
EMBO J. [巻]17 [頁]4744 -4752 (1998年) [査読] 有 [DOI]
[14]. K-252a-induced polyploidization and differentiation of a human megakaryocytic cell line, Meg-J: transient elevation and subsequent suppression of cyclin B1 and cdc2 expression in the process of polyploidization
Br. J. Haematol. [巻]102 [頁]812 -819 (1998年) [査読] 有 [DOI]
[15]. A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25
FEBS Lett. [巻]441 [頁]127 -131 (1998年) [査読] 有 [DOI]
[16]. The Protease Activity of a Calpain-like Cysteine Protease in Saccharomyces cerevisiae is Required for Alkaline Adaptation and Sporulation
Mol. Gen. Genet. [巻]260 [頁]559 -568 (1999年) [査読] 有 [DOI]
[17]. A radicicol-related macrocyclic nonaketide compound, antibiotic LL-Z1640-2, inhibits the JNK/p38 pathways in signal-specific manner
Biochem. Biophis. Res. Commun. [巻]257 [頁]19 -23 (1999年) [査読] 有 [DOI]
[18]. Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53
J. Biol. Chem. [巻]274 [頁]17003 -17010 (1999年) [査読] 有 [DOI]
[19]. beta3-Endonexin as a Novel Inhibitor of Cyclin A-Associated Kinase
Biochem. Biophys. Res. Commun. [巻]267 [頁]947 -952 (2000年) [査読] 有 [DOI]
[20]. Human p55CDC/Cdc20 Associates with Cyclin A and Is Phosphorylated by the Cyclin A-Cdk2 Complex
Biochem. Biophys. Res. Commun. [巻]268 [頁]530 -534 (2000年) [査読] 有 [DOI]
[21]. Metabolism of amyloid precursor protein in COS cells transfected with a beta-secretase candidate
Cytotechnology [巻]33 [頁]213 -219 (2000年) [査読] 有 [DOI]
[22]. Molecular cloning of PalBH, a mammalian homologue of the Aspergillus atypical calpain PalB
Biochim. Biophys. Acta [巻]1517 [頁]316 -319 (2001年) [査読] 有 [DOI]
[23]. Domain II of m-calpain is a Ca2+-dependent cysteine protease
FEBS Lett. [巻]501 [頁]111 -114 (2001年) [査読] 有 [DOI]
[24]. Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled
Biochem. Biophys. Res. Commun. [巻]286 [頁]771 -778 (2001年) [査読] 有 [DOI]
[25]. Both the Conserved and the Unique Gene Structure of Stomach-Specific Calpains Reveal Processes of Calpain Gene Evolution
J. Mol. Evol. [巻]53 [頁]191 -203 (2001年) [査読] 有 [DOI]
[26]. Limited Proteolysis of Filamin Is Catalyzed by Caspase-3 in U937 and Jurkat Cells
J. Biochem. [巻]130 [頁]535 -542 (2001年) [査読] 有
[27]. Coexpression of the CUG-binding protein reduces DM protein kinase expression in COS cells
JOURNAL OF BIOCHEMISTRY JAPANESE BIOCHEMICAL SOC [巻]130 [号]5 [頁]581 -587 (2001年) [査読] 有
[28]. Phosphorelay-regulated degradation of the yeast Ssk1p response regulator by the ubiquitin-proteasome system.
Molecular and cellular biology [巻]23 [号]18 [頁]6662 -71 (2003年) [DOI]
[29]. Paired-like homeodomain protein ESXR1 possesses a cleavable C-terminal region that inhibits cyclin degradation.
Oncogene [巻]23 [号]39 [頁]6590 -602 (2004年) [DOI]
[30]. Dictyostelium discoideum requires an Alix/AIP1 homolog, DdAlix, for morphogenesis in alkaline environments.
FEBS letters [巻]579 [号]7 [頁]1745 -50 (2005年) [DOI]
[31]. Aspergillus nidulans HOG pathway is activated only by two-component signalling pathway in response to osmotic stress.
Molecular microbiology [巻]56 [号]5 [頁]1246 -61 (2005年) [DOI]
[32]. Constitutive activation of the pH-responsive Rim101 pathway in yeast mutants defective in late steps of the MVB/ESCRT pathway.
Molecular and cellular biology [巻]25 [号]21 [頁]9478 -90 (2005年) [DOI]
[33]. Activation of the HOG pathway upon cold stress in Saccharomyces cerevisiae.
Journal of biochemistry [巻]139 [号]4 [頁]797 -803 (2006年) [DOI]
[34]. Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP.
The Journal of biological chemistry [巻]281 [号]16 [頁]11214 -24 (2006年) [DOI]
[35]. Identification and characterization of Arabidopsis gibberellin receptors.
The Plant journal : for cell and molecular biology [巻]46 [号]5 [頁]880 -9 (2006年) [DOI]
[36]. Suppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system.
The Journal of biological chemistry [巻]281 [号]27 [頁]18519 -31 (2006年) [DOI]
[37]. Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region.
The Journal of biological chemistry [巻]281 [号]39 [頁]28605 -14 (2006年) [DOI]
[38]. Human calpain 7/PalBH associates with a subset of ESCRT-III-related proteins in its N-terminal region and partly localizes to endocytic membrane compartments.
Journal of biochemistry [巻]143 [号]6 [頁]731 -45 (2008年) [DOI]
[39]. Isolation of hyperactive mutants of mammalian target of rapamycin.
The Journal of biological chemistry [巻]283 [号]46 [頁]31861 -70 (2008年) [DOI]
[40]. Pho85 kinase, a cyclin-dependent kinase, regulates nuclear accumulation of the Rim101 transcription factor in the stress response of Saccharomyces cerevisiae.
Eukaryotic cell [巻]9 [号]6 [頁]943 -51 (2010年) [DOI]
[41]. Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.
The Journal of clinical investigation [巻]120 [号]8 [頁]2672 -83 (2010年) [DOI]
[42]. Endocytosis of the aspartic acid/glutamic acid transporter Dip5 is triggered by substrate-dependent recruitment of the Rsp5 ubiquitin ligase via the arrestin-like protein Aly2.
Molecular and cellular biology [巻]30 [号]24 [頁]5598 -607 (2010年) [DOI]
[43]. Sphingolipids regulate the yeast high-osmolarity glycerol response pathway.
Molecular and cellular biology [巻]32 [号]14 [頁]2861 -70 (2012年) [査読] 有 [DOI]
[44]. Transient sequestration of TORC1 into stress granules during heat stress.
Molecular cell [巻]47 [号]2 [頁]242 -52 (2012年) [DOI]
[45]. Characterization of histidine-aspartate kinase HK1 and identification of histidine phosphotransfer proteins as potential partners in a Populus multistep phosphorelay.
Physiologia plantarum [巻]149 [号]2 [頁]188 -99 (2013年) [査読] 有 [DOI]
[46]. Selective activation of mTORC1 signaling recapitulates microcephaly, tuberous sclerosis, and neurodegenerative diseases.
Cell reports [巻]7 [号]5 [頁]1626 -1639 (2014年) [DOI]
[47]. Conserved Mode of Interaction between Yeast Bro1 Family V Domains and YP(X)nL Motif-Containing Target Proteins.
Eukaryotic cell [巻]14 [号]10 [頁]976 -82 (2015年) [DOI]
[48]. The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization.
The Journal of biological chemistry [巻]291 [号]4 [頁]1826 -40 (2016年) [査読] 有 [DOI]
[49]. Functional Divergence of Poplar Histidine-Aspartate Kinase HK1 Paralogs in Response to Osmotic Stress.
International journal of molecular sciences [巻]17 [号]12 (2016年) [査読] 有 [DOI]
[50]. Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCFβ-TRCP E3 Ubiquitin Ligase.
iScience [巻]5 [頁]1 -18 (2018年) [査読] 有 [DOI]
[51]. Nutrient Signaling via the TORC1-Greatwall-PP2A Pathway Is Responsible for the High Initial Rates of Alcoholic Fermentation in Sake Yeast Strains of Saccharomyces cerevisiae.
Applied and environmental microbiology [巻]85 [号]1 (2019年) [査読] 有 [DOI]
[52]. Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells.
Scientific reports [巻]9 [号]1 [頁]2799 (2019年) [査読] 有 [DOI]
[53]. TORC1 regulates autophagy induction in response to proteotoxic stress in yeast and human cells.
Biochemical and biophysical research communications [巻]511 [号]2 [頁]434 -439 (2019年) [査読] 有 [DOI]
[54]. New Insight into HPts as Hubs in Poplar Cytokinin and Osmosensing Multistep Phosphorelays: Cytokinin Pathway Uses Specific HPts.
Plants (Basel, Switzerland) [巻]8 [号]12 (2019年) [査読] 有 [DOI]
[55]. A glutamine sensor that directly activates TORC1.
Communications Biology (2021年) [査読] 有
[56]. Regulation of sphingolipid biosynthesis in the endoplasmic reticulum via signals from the plasma membrane in budding yeast.
The FEBS journal (2021年) [査読] 有 [DOI]
[57]. Coordinated regulation of TORC2 signaling by MCC/eisosome-associated proteins, Pil1 and tetraspan membrane proteins during the stress response.
Molecular microbiology [巻]117 [号]5 [頁]1227 -1244 (2022年) [査読] 有 [DOI]
[58]. The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets.
Cell reports [巻]39 [号]4 [頁]110721 (2022年) [査読] 有 [DOI]
[59]. 【知る・見る・活かす!シグナリング研究2015 シグナル伝達の要素発見から時空間ダイナミクスへ】(第1章)分子から見た新しいシグナリング機構 mTOR経路
実験医学 (株)羊土社 [巻]33 [号]10 [頁]1554 -1561 (2015年)
[60]. [Regulation of TOR complex 1 activity by stress].
Seikagaku. The Journal of Japanese Biochemical Society [巻]85 [号]3 [頁]205 -213 (2013年) [査読] 無
[61]. Stress granules: the last refuge of TORC1?
Cell cycle (Georgetown, Tex.) [巻]11 [号]20 [頁]3707 -8 (2012年) [DOI]
[62]. The signaling mechanism of ambient pH sensing and adaptation in yeast and fungi.
The FEBS journal [巻]279 [号]8 [頁]1407 -13 (2012年) [DOI]
[63]. Evaluation of mTOR function by a gain-of-function approach.
Cell cycle (Georgetown, Tex.) [巻]8 [号]4 [頁]573 -9 (2009年) [DOI]
[64]. [Regulation of eukaryotic His-Asp phosphorelay system by proteasome-dependent pathway].
Seikagaku. The Journal of Japanese Biochemical Society [巻]76 [号]12 [頁]1576 -8 (2004年)