光医学総合研究所 尖端生体イメージング研究部門 ナノスーツ開発研究分野
准教授
カワサキ ヒデヤ
河崎 秀陽

更新日: 2026/08/02
論文
[1]. Expression of Glycoprotein B (gB) Correlates With Poor Prognosis in Nasopharyngeal Carcinoma.
Cancer science (2026年) [査読] 有 [DOI]
[2]. A novel method of correlative light and electron microscopy in cryosectioning of bovine anterior pituitary tissue using NanoSuit CLEM.
The Journal of reproduction and development (2025年) [査読] 有 [DOI]
[3]. Capacitance compensation on a double-barrel nanopipette for improving current detection of scanning ion conductance microscopy
Ultramicroscopy Elsevier BV [巻]273 [頁]114149 -114149 (2025年) [査読] 有 [DOI]
[4]. Whole Slide Imaging-Free Supporting Tool for Cytotechnologists in Cervical Cytology.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [頁]100817 (2025年) [査読] 有
[5]. Visualization of Molluscum Contagiosum Virus in FFPE Skin Sections Using NanoSuit-CLEM: Ultrastructural Evidence of Viral Spread via Skin Barrier Disruption.
Immunity, inflammation and disease [巻]13 [号]6 [頁]e70212 (2025年) [査読] 有 [DOI]
[6]. Immunohistochemical and molecular evolutionary features of jejunoileal adenocarcinoma unveiled through comparative analysis with colorectal adenocarcinoma.
Neoplasia (New York, N.Y.) [巻]66 [頁]101180 (2025年) [査読] 有 [機関リポジトリ]
[7]. Pure Isolation, Culture, and Post-Injury Lineage Tracing of Mouse Visceral Pleural Mesothelial Cells.
American journal of respiratory cell and molecular biology (2026年) [査読] 有 [DOI]
[8]. A Case of Intrauterine Listeria Infection During Pregnancy: NanoSuit Imaging of Listeria monocytogenes in the Amniotic Membrane.
Cureus [巻]17 [号]7 [頁]e87792 (2025年) [査読] 有
[9]. Iron deposition in gastric black spots: Clinicopathological insights and NanoSuit-correlative light and electron microscopy analysis.
DEN open [巻]5 [号]1 [頁]e398 (2025年) [査読] 有
[10]. Autopsy Revealed an Extremely Rare Case of Hodgkin Lymphoma With Intranodal Extramedullary Hematopoiesis and Hemophagocytosis in a Patient With Severe Thrombocytopenia.
cureus springer nature [巻]17 [号]2 [頁]e79298 (2025年) [査読] 有
[11]. Integrin α8 is a useful cell surface marker of alveolar lipofibroblasts
BMC [巻]26 [頁]14 (2025年) [査読] 無
[12]. Transitions in Immunoassay Leading to Next-Generation Lateral Flow Assays and Future Prospects
MDPI [巻]12 [号]10 [頁]2268 (2024年) [査読] 有
[13]. A Case of Brunner's Gland Hyperplasia Accompanied by an Increase in Endocrine Cells and Endocrine Cell Micronests
springer nature [巻]16 [号]9 [頁]e68688 (2024年) [査読] 有
[14]. Enhancing cervical cancer cytology screening via artificial intelligence innovation
nature [巻]14 [号]1 [頁]19535 (2024年) [査読] 有
[15]. Cell-free DNA analysis for recurrent respiratory papillomatosis: A case report
Clinical case reports Wiley [巻]12 [号]8 [頁]e9268 (2024年) [査読] 有
[16]. Iron deposition in gastric black spots: Clinicopathological insights and NanoSuit-correlative light and electron microscopy analysis
DEN Open [巻]5 [号]1 [頁]e398 (2024年) [査読] 有
[17]. Development of an Undifferentiated Pleomorphic Sarcoma After Aortic Aneurysm Graft Replacement: A Case Report and Literature Review.
Cureus [巻]16 [号]6 [頁]e61530 (2024年) [査読] 有
[18]. Human induced pluripotent stem cells are resistant to human cytomegalovirus infection primarily at the attachment level due to the reduced expression of cell-surface heparan sulfate
JOURNAL OF VIROLOGY (2024年) [査読] 有 [DOI]
[19]. Phosphatidylcholine in bile-derived small extracellular vesicles as a novel biomarker of cholangiocarcinoma.
Cancer medicine Wiley Online Medicine (2023年) [査読] 有 [DOI]
[20]. Association between human papillomavirus particle production and the severity of recurrent respiratory papillomatosis.
Scientific reports [巻]13 [号]1 [頁]5514 (2023年) [査読] 有 [DOI]
[21]. Primary Cilia Are Frequently Present in Small Cell Lung Carcinomas but Not in Non-Small Cell Lung Carcinomas or Lung Carcinoids.
Laboratory investigation; a journal of technical methods and pathology [巻]103 [号]2 [頁]100007 (2023年) [査読] 有 [DOI]
[22]. Identifying Active Progeny Virus Particles in Formalin-Fixed, Paraffin-Embedded Sections Using Correlative Light and Scanning Electron Microscopy.
Laboratory investigation; a journal of technical methods and pathology [巻]103 [号]1 [頁]100020 (2023年) [査読] 有 [DOI]
[23]. An autopsy case of ovarian mucinous cystic tumor complicated by ovarian abscess and a review of the English literature.
Clinical case reports [巻]10 [号]11 [頁]e6507 (2022年) [査読] 有 [DOI]
[24]. Highly Sensitive and Quantitative Diagnosis of SARS-CoV-2 Using a Gold/Platinum Particle-Based Lateral Flow Assay and a Desktop Scanning Electron Microscope.
Biomedicines [巻]10 [号]2 (2022年) [査読] 有 [DOI]
[25]. Microscopy and biomimetics: the NanoSuit® method and image retrieval platform.
Microscopy (Oxford, England) [巻]71 [号]1 [頁]1 -12 (2022年) [査読] 有 [DOI] [機関リポジトリ]
[26]. Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis.
Journal of periodontal research [巻]57 [号]1 [頁]162 -172 (2022年) [査読] 有 [DOI]
[27]. Diagnosis of Ion-Exchange Resin Depositions in Paraffin Sections Using Corrective Light and Electron Microscopy-NanoSuit Method.
Diagnostics (Basel, Switzerland) [巻]11 [号]7 (2021年) [査読] 有 [DOI]
[28]. Identification and characterization of primary cilia-positive salivary gland tumours exhibiting basaloid/myoepithelial differentiation.
The Journal of pathology (2021年) [査読] 有 [DOI]
[29]. Difference in the distribution of tumor-infiltrating CD8+ T cells and FOXP3+ T cells between micronodular thymoma with lymphoid stroma and micronodular thymic carcinoma with lymphoid stroma.
Pathology international (2021年) [査読] 有 [DOI]
[30]. Gremlin-1 for the Differential Diagnosis of Idiopathic Pulmonary Fibrosis Versus Other Interstitial Lung Diseases: A Clinical and Pathophysiological Analysis.
Lung (2021年) [査読] 有 [DOI]
[31]. Combination of the NanoSuit method and gold/platinum particle-based lateral flow assay for quantitative and highly sensitive diagnosis using a desktop scanning electron microscope.
Journal of pharmaceutical and biomedical analysis [巻]196 [頁]113924 (2021年) [査読] 有 [DOI]
[32]. Prolonged activation of cytomegalovirus early gene e1-promoter exclusively in neurons during infection of the developing cerebrum.
Acta neuropathologica communications [巻]9 [号]1 [頁]39 (2021年) [査読] 有 [DOI]
[33]. ナノスーツ法による医療診断への応用
医学のあゆみ [巻]276 [号]7 [頁]740 -748 (2021年) [査読] 無
[34]. Metformin reduces pleural fibroelastosis by inhibition of extracellular matrix production induced by CD90-positive myofibroblasts.
American journal of translational research [巻]13 [号]11 [頁]12318 -12337 (2021年) [査読] 有
[35]. Telomere shortening in head and neck cancer: association between DNA demethylation and survival.
Journal of Cancer [巻]12 [号]8 [頁]2165 -2172 (2021年) [査読] 有 [DOI]
[36]. Epstein-Barr virus is a promoter of lymphoma cell metastasis.
Pathology [巻]52 [号]6 [頁]676 -685 (2020年) [査読] 有 [DOI]
[37]. Incidentally discovered mesenteric paraganglia as large as a lymph node in the sigmoid mesocolon, a possible origin of mesenteric paraganglioma.
Pathology international (2020年) [査読] 有 [DOI]
[38]. Living Organisms under an Electron Microscope: the NanoSuit® Method aiming for Medical and Industrial Applications
Journal of Photopolymer Science and Technology [巻]5 [頁]517 -522 (2020年) [査読] 有
[39]. Overexpression of Sal-like protein 4 in head and neck cancer: epigenetic effects and clinical correlations.
Cellular oncology (Dordrecht) (2020年) [査読] 有 [DOI] [機関リポジトリ]
[40]. Neuropeptide receptor genes GHSR and NMUR1 are candidate epigenetic biomarkers and predictors for surgically treated patients with oropharyngeal cancer.
Scientific reports [巻]10 [号]1 [頁]1007 (2020年) [査読] 有 [DOI]
[41]. CD248 and integrin alpha-8 are candidate markers for differentiating lung fibroblast subtypes.
BMC pulmonary medicine [巻]20 [号]1 [頁]21 (2020年) [査読] 有 [DOI]
[42]. 電子顕微鏡で観る昆虫: NanoSuit®法によるそのままの生物表面解析
昆蟲 昆虫学会 [巻]23 [号]4 [頁]145 -155 (2020年) [査読] 無
[43]. Long interspersed nuclear element 1 hypomethylation has novel prognostic value and potential utility in liquid biopsy for oral cavity cancer.
Biomarker research [巻]8 [頁]53 (2020年) [査読] 有 [DOI]
[44]. The NanoSuit method: a novel histological approach for examining paraffin sections in a nondestructive manner by correlative light and electron microscopy.
Laboratory investigation; a journal of technical methods and pathology [巻]100 [号]1 [頁]161 -173 (2020年) [査読] 有 [DOI]
[45]. Utility of Scanning Electron Microscopy Elemental Analysis Using the 'NanoSuit' Correlative Light and Electron Microscopy Method in the Diagnosis of Lanthanum Phosphate Deposition in the Esophagogastroduodenal Mucosa.
Diagnostics (Basel, Switzerland) MDPI [巻]10 [号]1 (2019年) [査読] 有 [DOI]
[46]. Nasal glomus tumor: A rare nasal tumor with diffuse and strongly positive synaptophysin expression.
Pathology international [巻]69 [号]11 [頁]672 -674 (2019年) [査読] 有 [DOI]
[47]. An Autopsy Case of a 5-Year-Old Child with Acute Pancreatitis Caused by Eosinophilic Granulomatosis with Polyangiitis-like Necrotizing Vasculitis.
Case reports in rheumatology [巻]2019 [頁]9053747 (2019年) [査読] 有 [DOI]
[48]. SALL2 Is a Novel Prognostic Methylation Marker in Patients with Oral Squamous Carcinomas: Associations with SALL1 and SALL3 Methylation Status.
DNA and cell biology [巻]38 [号]7 [頁]678 -687 (2019年) [査読] 有 [DOI]
[49]. Living Organisms under an Electron Microscope: the NanoSuit((R))
JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY [巻]32 [号]2 [頁]287 -290 (2019年) [査読] 有
[50]. Immunohistochemical examination using the pericyte marker myosin 1B in a perivascular myoid tumor of soft tissue with definitive pericytic differentiation.
Pathology international [巻]69 [号]4 [頁]246 -248 (2019年) [査読] 有 [DOI]
[51]. Aberrant Epigenetic Regulation in Head and Neck Cancer Due to Distinct EZH2 Overexpression and DNA Hypermethylation.
International journal of molecular sciences [巻]19 [号]12 (2018年) [査読] 有 [DOI]
[52]. Mitochondrial fission protein, dynamin-related protein 1, contributes to the promotion of hypertensive cardiac hypertrophy and fibrosis in Dahl-salt sensitive rats.
Journal of molecular and cellular cardiology [巻]121 [頁]103 -106 (2018年) [査読] 有 [DOI]
[53]. LTBP2 is secreted from lung myofibroblasts and is a potential biomarker for idiopathic pulmonary fibrosis.
Clinical science (London, England : 1979) [巻]132 [号]14 [頁]1565 -1580 (2018年) [査読] 有 [DOI]
[54]. MHC class I in dopaminergic neurons suppresses relapse to reward seeking.
Science advances [巻]4 [号]3 [頁]eaap7388 (2018年) [査読] 有 [DOI]
[55]. A case of a primary hepatic so-called adenosarcoma with heterotopic ossification: possibly of biliary adenofibroma origin.
Human pathology [巻]73 [頁]108 -113 (2018年) [査読] 有 [DOI]
[56]. Epigenetic modification of as a novel biomarker for the prognosis of early stage head and neck cancer.
Journal of Cancer [巻]9 [号]6 [頁]941 -949 (2018年) [査読] 有 [DOI]
[57]. Evaluation of epigenetic inactivation of vascular endothelial growth factor receptors in head and neck squamous cell carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine [巻]39 [号]7 [頁]1010428317711657 (2017年) [査読] 有 [DOI]
[58]. Phenotypic characterization of perivascular myoid cell neoplasms, using myosin 1B, a newly identified human pericyte marker.
Human pathology [巻]62 [頁]187 -198 (2017年) [査読] 有 [DOI]
[59]. A modified 'NanoSuit®' preserves wet samples in high vacuum: direct observations on cells and tissues in field-emission scanning electron microscopy.
Royal Society open science [巻]4 [号]3 [頁]160887 (2017年) [査読] 有 [DOI]
[60]. Pathogenesis of developmental anomalies of the central nervous system induced by congenital cytomegalovirus infection.
Pathology international [巻]67 [号]2 [頁]72 -82 (2017年) [査読] 有 [DOI]
[61]. Epigenetic silencing of is an independent predictor of poor survival in head and neck cancer.
Clinical epigenetics [巻]9 [頁]64 (2017年) [査読] 有 [DOI]
[62]. Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain.
Journal of visualized experiments : JoVE [号]113 (2016年) [査読] 有 [DOI]
[63]. Primary combined small and squamous cell carcinoma of the hypopharynx: A case report.
Molecular and clinical oncology [巻]4 [号]5 [頁]709 -714 (2016年) [査読] 有 [DOI]
[64]. Human papillomavirus-associated small cell carcinoma/neuroendocrine carcinoma of the oropharynx: a report of two cases.
SpringerPlus [巻]5 [号]1 [頁]1847 (2016年) [査読] 有 [DOI]
[65]. Cytomegalovirus initiates infection selectively from high-level β1 integrin-expressing cells in the brain.
The American journal of pathology [巻]185 [号]5 [頁]1304 -23 (2015年) [査読] 有 [DOI]
[66]. Aberrant fetal macrophage/microglial reactions to cytomegalovirus infection.
Annals of clinical and translational neurology [巻]1 [号]8 [頁]570 -88 (2014年) [査読] 有 [DOI]
[67]. Expression of β-Adrenoceptor Subtypes in Urothelium, Interstitial Cells and Detrusor of the Human Urinary Bladder.
Lower urinary tract symptoms [巻]5 [号]3 [頁]173 -80 (2013年) [査読] 有 [DOI]
[68]. Direct isolation of myofibroblasts and fibroblasts from bleomycin-injured lungs reveals their functional similarities and differences.
Fibrogenesis & tissue repair [巻]6 [号]1 [頁]15 (2013年) [査読] 有 [DOI]
[69]. Establishment of a novel mouse model of ulcerative colitis with concomitant cytomegalovirus infection: in vivo identification of cytomegalovirus persistent infected cells.
Inflammatory bowel diseases [巻]19 [号]9 [頁]1951 -63 (2013年) [査読] 有 [DOI]
[70]. An autopsy case of the Marburg variant of multiple sclerosis (acute multiple sclerosis).
Internal medicine (Tokyo, Japan) [巻]52 [号]16 [頁]1825 -32 (2013年) [査読] 有 [DOI]
[71]. Pluripotent stem cells are protected from cytomegalovirus infection at multiple points: implications of a new pathogenesis for congenital anomaly caused by cytomegalovirus.
Congenital anomalies [巻]52 [号]3 [頁]147 -54 (2012年) [査読] 有 [DOI]
[72]. Effects of intrapulmonary viral tropism and cytokine expression on the histological patterns of cytomegalovirus pneumonia.
Pathology international [巻]62 [号]9 [頁]628 -39 (2012年) [査読] 有 [DOI]
[73]. Mouse embryonic stem cells inhibit murine cytomegalovirus infection through a multi-step process.
PloS one [巻]6 [号]3 [頁]e17492 (2011年) [査読] 有 [DOI]
[74]. In vivo imaging assay for the convenient evaluation of antiviral compounds against cytomegalovirus in mice.
Antiviral research [巻]88 [号]1 [頁]45 -52 (2010年) [査読] 有 [DOI]
[75]. Aggressive progression of breast cancer with microscopic pulmonary emboli possessing a stem cell-like phenotype independent of its origin.
Pathology international [巻]60 [号]3 [頁]228 -34 (2010年) [査読] 有 [DOI]
[76]. Induction of cytomegalovirus-infected labyrinthitis in newborn mice by lipopolysaccharide: a model for hearing loss in congenital CMV infection.
Laboratory investigation; a journal of technical methods and pathology [巻]88 [号]7 [頁]722 -30 (2008年) [査読] 有 [DOI]
[77]. A case of primary cutaneous natural killer/T-cell lymphoma, nasal type, directly invading to the heart.
Leukemia & lymphoma [巻]49 [号]5 [頁]1008 -11 (2008年) [査読] 有 [DOI]
[78]. Roles of neural stem progenitor cells in cytomegalovirus infection of the brain in mouse models
PATHOLOGY INTERNATIONAL [巻]58 [号]5 [頁]257 -267 (2008年) [査読] 有 [DOI]
[79]. [Primary ureteral carcinoma composed of both transitional cell carcinoma and mucinous carcinoma: a case report].
Hinyokika kiyo. Acta urologica Japonica [巻]53 [号]12 [頁]883 -6 (2007年) [査読] 有
[80]. Enhancement of susceptibility of adult mouse brain to cytomegalovirus infection by infusion of epidermal growth factor.
Journal of neuroscience research [巻]85 [号]13 [頁]2981 -90 (2007年) [査読] 有 [DOI]
[81]. Cyclosporine inhibits mouse cytomegalovirus infection via a cyclophilin-dependent pathway specifically in neural stem/progenitor cells
Journal of virology [巻]81 [号]17 [頁]9013 -9023 (2007年) [査読] 有 [DOI]
[82]. Differential expression of the immediate-early 2 and 3 proteins in developing mouse brains infected with murine cytomegalovirus.
Archives of virology [巻]151 [号]11 [頁]2181 -96 (2006年) [査読] 有 [DOI]
[83]. Mouse embryonic stem cells are not susceptible to cytomegalovirus but acquire susceptibility during differentiation.
Birth defects research. Part A, Clinical and molecular teratology [巻]76 [号]2 [頁]115 -25 (2006年) [査読] 有 [DOI]
[84]. Neuropathogenesis in cytomegalovirus infection: indication of the mechanisms using mouse models.
Reviews in medical virology [巻]15 [号]5 [頁]327 -45 (2005年) [査読] 有 [DOI]
[85]. Cytomegalovirus infection inhibits the expression of N-methyl-D-aspartate receptors in the developing mouse hippocampus and primary neuronal cultures.
Acta neuropathologica [巻]109 [号]5 [頁]475 -82 (2005年) [査読] 有 [DOI]
[86]. Neuron-specific activation of murine cytomegalovirus early gene e1 promoter in transgenic mice.
The American journal of pathology [巻]163 [号]2 [頁]643 -52 (2003年) [査読] 有 [DOI]
[87]. Brain slice culture for analysis of developmental brain disorders with special reference to congenital cytomegalovirus infection.
Congenital anomalies [巻]43 [号]2 [頁]105 -13 (2003年) [査読] 有 [DOI]
[88]. The amount of immature glial cells in organotypic brain slices determines the susceptibility to murine cytomegalovirus infection.
Laboratory investigation; a journal of technical methods and pathology [巻]82 [号]10 [頁]1347 -58 (2002年) [査読] 有 [DOI]
[89]. Innate immune responses to cytomegalovirus infection in the developing mouse brain and their evasion by virus-infected neurons.
The American journal of pathology [巻]161 [号]3 [頁]919 -28 (2002年) [査読] 有 [DOI]
[90]. Reactivation of latent cytomegalovirus infection in mouse brain cells detected after transfer to brain slice cultures.
Journal of virology [巻]76 [号]14 [頁]7247 -54 (2002年) [査読] 有 [DOI]
[91]. Activation of murine cytomegalovirus immediate-early promoter in cerebral ventricular zone and glial progenitor cells in transgenic mice.
Glia [巻]35 [号]1 [頁]41 -52 (2001年) [査読] 有 [DOI]
[92]. Cytomegalovirus infection of the central nervous system stem cells from mouse embryo: a model for developmental brain disorders induced by cytomegalovirus.
Laboratory investigation; a journal of technical methods and pathology [巻]80 [号]9 [頁]1373 -83 (2000年) [査読] 有 [DOI]