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School of Medicine Faculty of Medicine Molecular Biology
Assistant Professor
大畑　樹也
OHATA Tatsuya

Last updated： 2025/05/01
Basic information on teaching staff
Career
2003/4/- 国立遺伝学研究所　　
2006/8/- オーストリア分子病理研究所(IMP)　
2009/10/- ケンブリッジ大学幹細胞研究センター（CSCR）
2012/9/- 現職
Research Areas
Life Science - Molecular biology
Research keywords
antisense RNA
X chromosome inactivation
long non-coding RNA
Epigenetics
EMT
cisNATs
Subject of research
[1]. 細胞の運命を左右する機能的非コードRNAの制御機構の解明
Research activities
Papers
[1]. Expression of Tumor Suppressor FHIT Is Regulated by the LINC00173-SNAIL Axis in Human Lung Adenocarcinoma.
International journal of molecular sciences [Volume]24 [Issue]23 （2023/） [Reviewed] Yes [DOI]
[2]. CCIVR2 facilitates comprehensive identification of both overlapping and non-overlapping antisense transcripts within specified regions.
Scientific reports [Volume]13 [Issue]1 [Page]14807 -14807 （2023/） [Reviewed] Yes [DOI]
[3]. p130RB2 positively contributes to ATR activation in response to replication stress via the RPA32-ETAA1 axis
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Elsevier BV [Volume]1870 [Issue]6 [Page]119484 -119484 （2023/） [Reviewed] Yes [DOI]
[4]. APOBEC3B expression is promoted by lincNMR collaborating with TGF-β-Smad pathway.
Carcinogenesis （2022/） [Reviewed] Yes [DOI]
[5]. Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair.
Biochimica et biophysica acta. Molecular cell research [Volume]1869 [Issue]11 [Page]119332 （2022/） [Reviewed] Yes [DOI]
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Research presentations
[1]. 2024/9/14 CCIVR facilitates comprehensive identification of cis-NATs with their structural characteristics and expression profiles 第８回X染色体研究会
[2]. 2024/6/13 CCIVR facilitates comprehensive identification of cis-NATs with their structural characteristics and expression profiles 第１７回日本エピジェネティクス研究会
[3]. 2023/12/8 CCIVR2 facilitates comprehensive identification of both overlapping and non-overlapping antisense transcripts within specified regions 第46回日本分子生物学会
[4]. 2023/11/21 CCIVR facilitates comprehensive identification of cis-NATs with their structural characteristics and expression profiles 第7回北陸エピジェネティクス研究会
[5]. 2023/11/15 CCIVR2 facilitates comprehensive identification of both overlapping and non-overlapping antisense transcripts within specified regions 第4回浜松医科大学研究交流会（リトリート）
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Prizes
[1]. 2009/8/ Gordon Research Conference (GRC) Epigenetics Best poster awards
[2]. 2005/9/ 日本遺伝学会 ベストペーパー賞
Memberships of academic societies
[1]. 日本分子生物学会
[2]. 日本RNA学会
[3]. 日本エピジェネティクス研究会
Educational activities
Allotted class
[1]. 生化学
[2]. 分子基礎医学
[3]. 生体構造・機能解析
[4]. 蛋白質研究法
Social activities
Social Contribution
[1]. 2022/8/10- Academic Summer School 2022 "Extracting DNA from Broccoli"