Faculty Information : Hamamatsu University School of Medicine

Basic information on teaching staff

Career

1991/- 1998/ Nippon Roche Research Center Researcher
1998/- 1999/ AGENE Research Institute Researcher
1999/- 2001/ Lawrence Berkeley National Lab. Research associate
2001/- 2007/ Nagoya City University Assistant Professor
2007/- 2010/ Nagoya City University
2010/2/- 2010/6/ Nagoya City University Lecturer
2010/7/- Hamamatsu University School of Medicine Molecular Biology Associate Professor

Academic degrees

Yamagata University
Obihiro University of Agriculture and Veterinary Medicine

Research Areas

Life Science - Molecular biology

Life Science - Medical biochemistry

Subject of research

[1]. DNA損傷修復時における細胞内応答の解析

Research Projects (Competitive Research Funds)

[1]. Elucidation of the nucleotide excision repair mechanism involved in ICI susceptibility and its medical application
[2]. 先天性角化異常症細胞のゲノム不安定性を招く新規ヌクレオチド除去修復因子の欠損

Research activities

Papers

[1]. Expression of Tumor Suppressor FHIT Is Regulated by the LINC00173-SNAIL Axis in Human Lung Adenocarcinoma
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES [Volume]24 [Issue]23 （2023/） [Reviewed] Yes [DOI]

[2]. p130RB2 positively contributes to ATR activation in response to replication stress via the RPA32-ETAA1 axis
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH [Volume]1870 [Issue]6 （2023/） [Reviewed] Yes [DOI]

[3]. APOBEC3B expression is promoted by lincNMR collaborating with TGF-β-Smad pathway.
Carcinogenesis （2022/） [Reviewed] Yes [DOI]

[4]. CCIVR facilitates comprehensive identification of cis-natural antisense transcripts with their structural characteristics and expression profiles.
Scientific reports [Volume]12 [Issue]1 [Page]15525 （2022/） [Reviewed] Yes [DOI]

[5]. Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair.
Biochimica et biophysica acta. Molecular cell research [Volume]1869 [Issue]11 [Page]119332 -119332 （2022/） [Reviewed] Yes [DOI]

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Research presentations

[1]. 2024/11/7 PRMT4 facilitates XPF-ERCC1 heterodimer assembly and maintains nucleotide excision repair activity 第９７回日本生化学会大会

[2]. 2024/11/7 PRMT4 facilitates XPF-ERCC1 heterodimer assembly and maintains nucleotide excision repair activity 第９７回日本生化学会大会

[3]. 2023/12/6 Arginine methylation of XPF by CARM1 promotes complex formation with ERCC1 and DNA repair 第４６回日本分子生物学会年会

[4]. 2022/11/30 Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repair 第45回日本分子生物学会年会

[5]. 2022/9/29 Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate NER 第81回日本癌学会学術総会

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Memberships of academic societies

[1]. 日本癌学会

[2]. 日本分子生物学会

[3]. 日本生化学会

[4]. 日本放射線影響学会

Educational activities

Allotted class

[1]. 分子基礎医学

[2]. 生化学

[3]. 生化学実習