Faculty Information : Hamamatsu University School of Medicine

Basic information on teaching staff

Other affiliation

[1]. Institute of Photonics Medicine Division of Research and Development in Photonics Technology Biomedical Instrumentation Laboratory 准教授
[2]. Institute of Photonics Medicine International Mass Imaging Center 准教授

Career

2003/4/- 2004/3/ The Japan Society for the Promotion of Science (Tokyo University of Pharmacy and Life Science) Research Fellow
2004/4/- 2005/3/ The Japan Society for the Promotion of Science (The University of Tokyo) Research Fellow
2005/4/- 2009/2/ MITSUBISHI KAGAKU INSTITUTE OF LIFE SCIENCES Research Fellow
2009/3/- 2018/10/ Department of Tumor Pathology, Hamamatsu University School of Medicine Assistant Professor
2018/11/- 現職

Academic background

2000/3/ skipped a grade Tokyo University of Pharmacy and Life Science, Department of Life Science, Molecular Life Science Course (Allowed to skip fourth grade of the Faculty to enter the Graduate School)
2002/3/ completed Tokyo University of Pharmacy and Life Science, Graduate School of Life Science (M.Sc., Life Science)
2004/3/ completed Tokyo University of Pharmacy and Life Sciences 生命科学研究科博士課程修了

Academic degrees

Doctor of Life Science Tokyo University of Pharmacy and Life Science

Current state of research and teaching activities

We are conducting research focusing on post-translational modifications of proteins and their effects, and machine learning including generative AI using multidimensional imaging data, with the aim of elucidating disease pathology and developing therapeutic drugs.

Research Areas

Life Science - Anatomy

Life Science - Pathophysiologic neuroscience

Life Science - Cell biology

Life Science - Morphology and anatomical structure

Research keywords

Machine Learning/AI

post-translational modifications

Drug Discovery

Mass Spectrometry Imaging

Subject of research

[1]. Drug Discovery Empowered by Spatial Omics and Artificial Intelligence
[2]. Post-translational modification of proteins and therapeutic drug development

Research activities

Papers

[1]. Structure-dependent reactive oxygen species generation by scintillator-free X-ray-activated porphyrins: insights into charge effects and internal conversion quantum yield.
Journal of radiation research [Volume]2 [Issue]67 [Page]210 -220 （2026/） [Reviewed] Yes

[2]. IgE-dependent anaphylaxis is regulated by sphingolipid binding to activating and inhibitory CD300 family members.
Cell reports [Volume]45 [Issue]3 [Page]117054 （2026/） [Reviewed] Yes

[3]. Myocardial testosterone glucuronide and disease phenotypes in hypertrophic cardiomyopathy.
ESC heart failure [Volume]13 [Issue]1 （2026/） [Reviewed] Yes [DOI]

[4]. LC-MS/MS and high-spatial single-cell MSI reveal selective downregulation of PC(16:0_16:0) and PC(18:0_18:1) due to mPGES-1 knockdown in hormone-resistant prostate cancer cell line
ANALYTICAL AND BIOANALYTICAL CHEMISTRY （2025/） [Reviewed] Yes [DOI]

[5]. Ion Mobility-Mass Spectrometry Imaging: Advances in Biomedical Research
BioTech (Basel) [Volume]14 [Issue]4 [Page]98 （2025/） [Reviewed] Yes [DOI]

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Research presentations

[1]. 2025/9/25 Initiatives and Achievements for Cadaver Surgical Training at Hamamatsu University School of Medicine The 22th Keihoku-Hamamatsu Joint Medical Symposium

[2]. 2025/7/ 乳癌細胞株におけるubiquitin-like 3(UBL3)の増殖・浸潤への寄与日本乳癌学会総会

[3]. 2024/3/23 脳組織の空間オミクスに対する生成AIを用いたデータ補間第129回日本解剖学会総会

[4]. 2024/3/23 身近な色覚多様性を考える〜解剖学教員のケースレポート〜第129回日本解剖学会総会

[5]. 2023/12/22 Approach to Mass Spectrometry Imaging Analysis Using Deep Generative Model - Toward Integrated Spatial Omics Analysis 日本質量分析学会イオン反応研究会

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Memberships of academic societies

[1]. 2026/4/- 量子生命科学会

[2]. 2023/7/- The Mass Spectrometry Society of Japan

[3]. 2023/5/- Japanese Society for Biomedical Mass Spectrometry

[4]. 2020/1/- The Japanese Association of Anatomists

[5]. 2019/1/- Japanese Association of Medical Artificial intelligence

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Educational activities

Allotted class

[1]. 解剖学I（骨学）

[2]. 解剖学I（組織学）

[3]. 解剖学I（解剖学総論）

[4]. 解剖学II（系統解剖学）

Social activities

Social Contribution

[1]. 2026/2/- 2026/2/ 国際マスイメージングセンター見学会

[2]. 2025/11/7- 2025/11/7 静岡高校生徒見学会

[3]. 2025/6/10- 2025/6/10 授業解放解剖学I（神経解剖学総論）

[4]. 2025/2/21- 2025/2/21 国際マスイメージングセンター見学会

[5]. 2024/11/8- 2024/11/8 静岡高校生徒見学会

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