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School of Medicine Faculty of Nursing Basic Nursing
Professor
秋田　天平
AKITA Tenpei

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Last updated： 2026/04/26
Basic information on teaching staff
Career
2001/4/- 2004/3/ the Japan Society for the Promotion of Science Postdoctoral Research Fellow of the Japan Society for the Promotion of Science
2004/4/- 2007/3/ Nagoya University of Arts and Sciences Postdoctoral fellow
2007/3/- 2008/6/ Centre for Public Health, Okazaki City Medical Association Clinical doctor
2008/6/- 2012/11/ National Institute for Physiological Sciences Department of Cell Physiology Assistant Professor
2012/11/- 2021/12/ Hamamatsu University School of Medicine Department of Neurophysiology Associate Professor
2022/1/- Hamamatsu University School of Medicine Division of Health Science Department of Basic Nursing Professor
Academic background
1996/3/ graduated Saga Medical School School of Medicine Faculty of Medicine
2001/1/ completed Nagoya University Graduate School of Medicine Department of Physiology
Academic degrees
Doctor(Medicine) Nagoya University
Licenses and qualifications
[1]. 1996/4/23 医師免許
[2]. 2015/1/1 日本生理学会認定生理学エデュケーター
[3]. 2024/1/1 日本生理学会認定卓越生理学エデュケーター
Research Areas
Life Science - Physiology
Life Science - Function of nervous system
Life Science - Pathophysiologic neuroscience
Research keywords
Pathophysiology
Neurophysiology
Cell physiology
membrane excitability regulation
epilepsy
ion channels
calcium nanodomains
cell volume regulation
neural development
intercellular signal transmission
Subject of research
[1]. イオンチャネルによる細胞膜興奮性制御の生理機構と病態
[2]. イオンチャネルによる神経細胞移動の駆動と細胞間情報伝達
Research Projects (Competitive Research Funds)
[1]. Investigation of the regulatory mechanism of cellular excitability by functional coupling between chloride channels and other types of ion channels in nano- or microdomains
[2]. Exploration of Therapeutic Target Molecules for Developmental and Epileptic Encephalopathies with Decreased Repetitive Firing Activity of Pyramidal Neurons
[3]. Elucidating regulatory mechanisms for neural precursor development by voltage-dependent ion channels
[4]. Exploration of the integrated physiological mechanism of membrane excitability regulation through analyses of disease-causing gene mutations.
[5]. Exploring the mechanisms for neuronal migration and intercellular communication steered by ion channels in the embryonic brain.
[6]. Mechanisms and roles of volume-sensitive anion channel activation mediated by chemical transmitters released in response to cell membrane stretch.
[7]. Research on the activation mechanism of volume-sensitive ion channels in neurons and glia.
[8]. Volume-sensor anion channel and mechano-sensor cation channel: Their functional modal shifts and molecular interaction.
[9]. Functional triadic coupling of ryanodine receptors and calcium channels to effector molecules in neurons
Research activities
Papers
[1]. Static magnetic field stimulation enhances shunting inhibition via a SLC26 family Cl−channel, inducing intrinsic plasticity
The Journal of Neuroscience Society for Neuroscience [Volume]44 [Issue]9 [Page]e1324222024 （2024/） [Reviewed] Yes [DOI]
[2]. 新カリキュラム施行から1年　看護基礎教育の今を探る　Part３　新年度から新たに取り組む科目の展望　「アクティブラーナーを育てる」
看護展望 メヂカルフレンド社 [Volume]48 [Issue]4 [Page]148 -152 （2023/） [Reviewed] No
[3]. A novel de novo KCNB1 variant altering channel characteristics in a patient with periventricular heterotopia, abnormal corpus callosum, and mild seizure outcome.
Journal of Human Genetics Springer Nature [Volume]68 [Issue]1 [Page]25 -31 （2023/） [Reviewed] Yes [DOI]
[4]. Taurine depletion during fetal and postnatal development blunts firing responses of neocortical layer II/III pyramidal neurons.
Frontiers in Molecular Neuroscience [Volume]15 [Page]806798 （2022/） [Reviewed] Yes [DOI]
[5]. WNK3 kinase maintains neuronal excitability by reducing inwardly rectifying K+ conductance in layer V pyramidal neurons of mouse medial prefrontal cortex.
Frontiers in Molecular Neuroscience [Volume]15 [Page]856262 （2022/） [Reviewed] Yes [DOI]
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Bibliography
[1]. 2020/7/1 "Regulation of neuronal cell migration and cortical development by chloride transporter activities" In Neuronal Chloride Transporters in Health and Disease Academic Press, Elsevier
[2]. 2013/4/5 脳科学辞典「塩素チャネル」 日本神経科学学会
[3]. 2012/ "Patch-clamp techniques: general remarks." In Patch Clamp Techniques: From Beginning to Advanced Protocols Springer
[4]. 2011/5/ 最新パッチクランプ実験技術法　「２章　パッチクランプ法総論」 吉岡書店
[5]. 2000/ "Enhancement of neurotransmitter release by activation of ryanodine receptors after Ca2+-dependent priming at motor nerve terminals." In Slow Synaptic Responses and Modulation Springer-Verlag
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Research presentations
[1]. 2026/3/11 The role of voltage-gated Cl− channels in driving epileptiform synchronous periodic firing activity in primary cortical neuronal circuits The 103rd Annual Meeting of The Physiological Society of Japan
[2]. 2025/10/17 大脳皮質神経群のてんかん様同期的周期的発火活動が電位依存性Cl－チャネルにより駆動される可能性 第72回中部日本生理学会
[3]. 2025/3/7 錐体神経連続発火活動の低下を伴う発達性てんかん性脳症に対する治療標的分子の探索 てんかん治療研究振興財団　第36回研究報告会
[4]. 2024/3/28 A de novo mutation of the voltage-gated K+ channel Kv2.1 in a patient with cerebral cortical dysplasia. The 101st Annual Meeting of The Physiological Society of Japan
[5]. 2023/10/20 電位感受性K＋チャネルKv2.1の新生突然変異に伴って生じた大脳皮質形成異常 第70回中部日本生理学会
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Prizes
[1]. 2012/3/29 The 89th Annual Meeting of The Physiological Society of Japan Poster Award
Memberships of academic societies
[1]. The Physiological Society of Japan
[2]. THE JAPAN NEUROSCIENCE SOCIETY
[3]. JAPAN EPILEPSY SOCIETY
Committee Career
[1]. 2024/1/1- The Physiological Society of Japan 卓越生理学エデュケーター
[2]. 2015/1/1- 2023/12/31 The Physiological Society of Japan 生理学エデュケーター
[3]. 2012/3/30- The Physiological Society of Japan 評議員
Educational activities
Allotted class
[1]. Pathophysiology
[2]. Pathology
[3]. Anatomy and PhysiologyⅠ
[4]. Anatomy and Physiology II
[5]. Anatomy and PhysiologyⅢ
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Social activities
Social Contribution
[1]. 2025/6/4- 2025/6/11 高校生授業開放
[2]. 2024/6/5- 2024/6/12 高校生授業開放
[3]. 2023/6/7- 2023/6/14 高校生授業開放